Having read recently that benzodiapines, amitryptyline and other anticholinergic drugs majorly increase the risk of developing cognitive decline and dementias, in particular Alzheimers, I try not to take amitryptyline at night to assist in getting me to sleep and keeping me asleep but the fibromyalgia pain that wakes me and is present every morning really does get me down.
Anticholinergic drugs are a huge group of medications including antihistamines and tricyclic antidepressants, increasing risk even at low doses. With me, it’s my right arm and shoulder that wake me, along with hands, wrists and fingers, knees and ankles. Weirdly it used to be my left arm for five years but recently it swapped over. The pain never manifests in the same way during waking hours, when it isn’t characterised by stabbing and shooting electrical sensations but more deep muscular aches and stiffness.
I’m doing 10 minutes of exercise and warm baths before bed, both recommended strategies. It seems every medication used against fibromyalgia, other than CBD oil, is a loaded weapon that could have a devastating payload to deliver further down the line. But we have to play Russian Roulette if we want help in the here and now.